The Inflammasome Components NLRP3 and ASC Act in Concert with IRGM To Rearrange the Golgi Apparatus during Hepatitis C Virus Infection

نویسندگان

چکیده

Numerous pathogens can affect cellular homeostasis and organelle dynamics. Hepatitis C virus (HCV) triggers Golgi fragmentation through the immunity-related GTPase M (IRGM), a resident protein, to enhance its lipid supply for replication.

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 2021

ISSN: ['1098-5514', '1070-6321', '0022-538X']

DOI: https://doi.org/10.1128/jvi.00826-20